18 Oct 2025

The lab traveled to Boston, MA for the American Society of Human Genetics Annual Meeting (October 14–18, 2025), with a platform talk and four posters:

  • Platform talk (Floris): Telomere dysfunction promotes remote recombination events between telomeres, centromeres and ribosomal DNA that are catalyzed by long-range chromatin interactions
  • Poster (Yi-An): Ultra-long-range telomeric chromatin interactions are enriched in cancer cells and involve repetitive elements
  • Poster (Yue & Mimi): Telomere dysfunction and spatial proximity cooperate to shape the genomic evolution of pre-cancerous astrocytes
  • Poster (Rhyker): Sequence annotation using KaryoScope facilitates the rapid and accurate classification and quantification of repeats, genes, and other genomic elements
  • Poster (Sharvari): Utilizing alignment-free classification of cell-free DNA sequencing reads to monitor tumor burden in primary brain tumors