the barthel laboratory

Welcome to the Barthel Laboratory. Set to the backdrop of the stunning Sonoran Desert, we study the role of telomere dysfunction in brain cancer (glioma) development and evolution. We are a part of the Cancer and Cell Biology Division at the Translational Genomics Research Institute (TGen) and the Department of Computational and Quantitative Medicine (DCQM) at the Beckman Research Institute (BRI) at City of Hope (COH).

Read more about our research.

We are actively looking for new graduate students, postdoctoral fellows and staff to join our team. Please click here for more information.

News
One year anniversary lab lunch
We reached a first milestone: the lab is officially one year old! We decided to go out for lunch to celebrate.
Posted 30 Sep 2022 by Floris Barthel
CSHL Brain Tumor Course
Thanks to the invitation of Dr. Sadhan Majumder I had the opportunity to teach at this year’s Cold Spring Harbor Laboratory Brain Tumor course. The students and faculty were outstanding: everyone was fully engaged and embracing every opportunity to learn new things.
Posted 08 Aug 2022 by Floris Barthel
Lab photos
The lab was overdue a new photo so we asked Jeff Watkins to help us out and shoot us some new ones. Thanks Jeff!
Posted 08 Jun 2022 by Floris Barthel
Lab Dinner at Pemberton
The spring weather in Phoenix has been incredible. Had the chance to take the lab and friends out for dinner at Pemberton, which is a hip food truck venue just a few minutes walking from the lab. Great times. Need to start taking photos more often though, because I missed out on documenting several other of these fun social events we had!
Posted 25 Feb 2022 by Floris Barthel
Publications
PDPN marks a subset of aggressive and radiation-resistant glioblastoma cells
Published 10 Aug 2022
Glioma progression is shaped by genetic evolution and microenvironment interactions
Published 09 Jun 2022
Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response
Published 30 Sep 2021
Spatial concordance of DNA methylation classification in diffuse glioma
Published 28 May 2021
Open positions
Computational Scientist
Open - Posted 24 Feb 2022