Welcome to the Barthel Laboratory. Set to the backdrop of the stunning Sonoran Desert in Arizona, we utilize state-of-the-art genomic approaches such as long-read sequencing and spatial transcriptomics to study the development and evolution of glial brain tumors (gliomas). The lab has a particular interest in the fundamental role of telomere dysfunction in tumor development, but is generally interested in all aspects of tumor evolution. Other interests include (but are not limited to) longitudinal studies of therapy response assessed by genomic analyses of tissue samples and liquid biopsies.
Read more about our research.